Research at Mass General

Research at Massachusetts General Hospital began over 200 years ago with the first public demonstration of ether as a general anesthetic for surgery.

The Mass General Research Institute is now home to the largest hospital-based research program in the United States, with a budget of more than $850 million, and was ranked the #1 healthcare institution for research by the Nature Index based on the number of publications our scientists had in journals of significance.

The Research Institute is built on a culture of excellence, compassion and groundbreaking scientific achievement. Our researchers work side-by-side with physicians—in the lab, in the clinic and at the bedside—harnessing the latest technological advancements to foster discovery at every stage.

Research at Mass General takes place in over 30 departments, centers and institutions that are interwoven throughout the hospital. It covers the full spectrum of biomedicine, from fundamental discovery science in our Department of Molecular Biology to the over 1,200 clinical trials supported by our Division for Clinical Research.

The Mass General Research Institute is powered by a vibrant community of more than 10,000 people who are dedicated to pushing the boundaries of science and medicine to improve the care we provide to patients at Mass General and across the globe.